Research resources
Longevity research resources.
Better questions begin here.
A practical starting point for exploring evidence, understanding terminology, and preparing a useful contribution.
PubMed ↗
Find biomedical papers, abstracts, publication details, and links to full text where available.
Full-text readingPubMed Central ↗
Read publicly available full-text research articles. Check the original publication date and any updates.
Human studiesClinicalTrials.gov ↗
Explore registered studies. Look for eligibility, study design, recruitment status, and posted results.
Data discoveryCALERIE data resource ↗
Read the resource paper and follow its access information for research use of trial-derived molecular data.
Independent resources are provided for research discovery. Inclusion does not imply a partnership or endorsement.
A reading companion
Before you share
the headline.
Use these questions to prepare a paper discussion or structure an article. The aim is a conclusion that stays close to the evidence.
Turn your reading into a contribution ↗- Define the question.What was the study trying to establish? Is that the same claim made in the headline?
- Identify the model.Cells, animals, or people? Which population, tissue, or condition was studied?
- Find the comparison.What was the control? What other explanation could account for the result?
- Read the outcome.Was it a molecular marker, physical function, disease incidence, or survival?
- Look for limitations.Check sample size, follow-up, missing data, uncertainty, and reported harms.
- State the next question.What independent test or additional evidence would strengthen the conclusion?
A shared vocabulary
Terms you will encounter.
Healthspan & lifespan
Lifespan concerns how long life lasts. Healthspan concerns the period of life spent in good health or function; a study should say how it defines and measures that idea.
Biomarker & clinical outcome
A biomarker is a measured biological characteristic. A clinical outcome concerns how a person feels, functions, or survives. An article should explain whether the chosen biomarker reliably supports the clinical claim.
Preclinical & clinical research
Preclinical work includes experiments before testing a proposed treatment in people. Clinical research involves human participants. Both can be informative, but they answer different questions.
Hypothesis & result
A hypothesis proposes an explanation or prediction. A result reports what was observed in an investigation. A good discussion makes it possible to tell which is which.
Reproducibility
For a contribution to LERI, explain what someone else would need to examine or repeat the analysis: data access, methods, assumptions, and the conditions of the comparison.
The questions behind the science
Life extension.
How far can research take us?
Explore longevity, immortality, and the ambition to stop or reverse aging—with clear definitions and links to the evidence.